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                     1925  | 
                                 
                     Established Takara Shuzo Co., Ltd  | 
                        
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                     1970  | 
                                 
                     Launched the Central Research Laboratories in the city of Otsu, Shiga  | 
                        
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                     1973  | 
                                 
                     Developed and commercialized an artificial cultivation method for Bunashimeji mushrooms  | 
                        
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                     1979  | 
                                 
         
                    Commenced sales of the first domestically produced restriction enzymes as reagents for genetic engineering research Entered Biomedical Business  | 
                        
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                     1988  | 
                                 
         
                    Acquired exclusive distribution rights in Japan for a gene amplification system using PCR technology  | 
                        
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                     1993  | 
                                 
                     Obtained worldwide PCR-related patent licenses to manufacture PCR products  | 
                        
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                     1993  | 
                                 
         
                    Established Takara Biotechnology (Dalian) Co., Ltd. in China, in order to manufacture life science research reagents  | 
                        
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                     1995  | 
                                 
                     Established Takara Biomedical Europe S.A.(currently Takara Bio Europe S.A.S) in Paris, France, in order to sell life science research reagents  | 
                        
|  
                     1995  | 
                                 
         
                    Developed the RetroNectin® Method for highly-efficient retrovial transduction in hematopoietic stem cells  | 
                        
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                     1995  | 
                                 
                     Established Bohan Biomedical Inc.(currently Takara Korea Biomedical Inc.) in Seoul, Korea  | 
                        
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                     2000  | 
                                 
         
                    Established DRAGON GENOMICS Co., LTD. (merged to Takara Bio in 2002) Launched full-scale genetic analysis services  | 
                        
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                     2001  | 
                                 
                     Established Mizuho Norin Co., Ltd. (transferred to YUKIGUNI MAITAKE CO., LTD. in 2019)  | 
                        
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                     2002  | 
                                 
                     Established Takara Bio Inc. in the city of Otsu, Shiga, split off from Takara Shuzo, Co., Ltd.  | 
                        
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                     2004  | 
                                 
                     Established Takara Biomedical Technology (Beijing) Co., Ltd. in China  | 
                        
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                     2004  | 
                                 
                     Listed on the TSE Mothers Index  | 
                        
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                     2005  | 
                                 
         
                    Acquired U.S.-based Clontech Laboratories, Inc. (currently Takara Bio USA, Inc.)  | 
                        
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                     2007  | 
                                 
                     Established KINOKO CENTER KIN INC. in Okinawa (transferred to YUKIGUNI MAITAKE CO., LTD. in 2019)  | 
                        
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                     2011  | 
                                 
                     Established DSS Takara Bio India Pvt. Ltd. in New Delhi, India  | 
                        
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                     2014  | 
                                 
         
                    Acquired Cellectis AB (currently Takara Bio Europe AB) in Göteborg, Sweden  | 
                        
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                     2014  | 
                                 
         
                    Launched the Center for Gene and Cell Processing Started CDMO business providing manufacturing and development support services for regenerative medicine products, etc.  | 
                        
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                     2015  | 
                                 
         
                    Launched new research facility in Kusatsu, Shiga Headquarters functions relocated  | 
                        
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                     2016  | 
                                 
                     Changed listing to the First Section of the TSE  | 
                        
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                     2017  | 
                                 
                     Acquired Rubicon Genomics, Inc. by wholly-owned subsidiary Takara Bio USA Holdings, Inc., thereafter merged to Takara Bio USA, Inc.  | 
                        
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                     2017  | 
                                 
                     Acquired Wafergen Bio-systems, Inc. by wholly-owned subsidiary Takara Bio USA Holdings, Inc., thereafter merged to Takara Bio USA, Inc.  | 
                        
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                     2018  | 
                                 
                     Designated NY-ESO-1 siTCR~{TM} as a product under the "SAKIGAKE Designation System".  | 
                        
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                     2019  | 
                                 
                     Transferred the AgriBio Business  | 
                        
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                     2020  | 
                                 
         
                    Launched the Center for Gene and Cell Processing II  | 
                        
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                     2020  | 
                                 
         
                    Launched Takara SARS-CoV-2 Direct PCR kit, an in vitro diagnostic  | 
                        
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                     2020  | 
                                 
                     NY-ESO-1 siTCR~{TM} designated as an Orphan Regenerative Medicine  | 
                        
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                     2021  | 
                                 
                     Established Takara Bio UK Ltd.  | 
                        
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                     2021  | 
                                 
                     Takara Bio USA Inc. relocated its headguarters to San Jose, California, USA  | 
                        
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                     2022  | 
                                 
                     Changed to the Prime Market of the Tokyo Stock Exchange  |